Clustering of Helicobacter pylori VacA in Lipid Rafts, Mediated by Its Receptor, Receptor-Like Protein Tyrosine Phosphatase β, Is Required for Intoxication in AZ-521 Cells

Helicobacter pylori vacuolating cytotoxin, VacA, induces multiple effects on epithelial cells through different cellular events: one involves pore formation, leading to vacuolation, mitochondrial damage, and apoptosis, and the second involves cell signaling, resulting in stimulation of proinflammato...

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Detalhes bibliográficos
Main Authors: Nakayama, Masaaki, Hisatsune, Jyunzo, Yamasaki, Eiki, Nishi, Yoshito, Wada, Akihiro, Kurazono, Hisao, Sap, Jan, Yahiro, Kinnosuke, Moss, Joel, Hirayama, Toshiya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698068/
https://ncbi.nlm.nih.gov/pubmed/17030583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00356-06
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