The dissociation of acetylcholine from open nicotinic receptor channels
Ligand-gated ion channels bind agonists with higher affinity in the open than in the closed state. The kinetic basis of this increased affinity has remained unknown, because even though the rate constants of agonist association to and dissociation from closed receptors can be estimated with reasonab...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC61175/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11717464/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.251402498 |
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