Serum choline activates mutant acetylcholine receptors that cause slow channel congenital myasthenic syndromes

We have found that mutant acetylcholine receptor channels (AChRs) that cause slow-channel congenital myasthenic syndromes are activated by serum and that the high frequency of openings in serum is reduced by treatment with choline oxidase. Thus, slow-channel congenital myasthenic syndrome AChRs at t...

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Bibliographic Details
Main Authors: Zhou, Ming, Engel, Andrew G., Auerbach, Anthony
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC17912/
https://ncbi.nlm.nih.gov/pubmed/10468632
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