Fluoxetine is neuroprotective in slow-channel congenital myasthenic syndrome

The slow-channel congenital myasthenic syndrome (SCS) is an inherited neurodegenerative disease caused mutations in the acetylcholine receptor (AChR) affecting neuromuscular transmission. Leaky AChRs lead to Ca(2+) overload and degeneration of the neuromuscular junction (NMJ) attributed to activatio...

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Publicat a:Exp Neurol
Autors principals: Zhu, Haipeng, Grajales-Reyes, E., Vázquez, Vivianette Alicea, Robinson, KaReisha, Pytel, Peter, Báez-Pagán, Carlos A, Lasalde-Dominicci, Jose A, Gomez, Christopher M
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430442/
https://ncbi.nlm.nih.gov/pubmed/25448156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.10.008
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