The dissociation of acetylcholine from open nicotinic receptor channels
Ligand-gated ion channels bind agonists with higher affinity in the open than in the closed state. The kinetic basis of this increased affinity has remained unknown, because even though the rate constants of agonist association to and dissociation from closed receptors can be estimated with reasonab...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC61175/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11717464/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.251402498 |
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