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Optimization of carvedilol solid lipid nanoparticles: An approach to control the release and enhance the oral bioavailability on rabbits

Solid lipid nanoparticles (SLNs) are prospective carriers for oral delivery of poorly soluble drugs with low bioavailability. Therefore, the study aimed at developing carvedilol (CVD) in SLNs to control its release and enhance its bioavailability in the management of hypertension, and cardiac diseas...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: El-Say, Khalid Mohamed, Hosny, Khaled Mohamed
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117064/
https://ncbi.nlm.nih.gov/pubmed/30161251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203405
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