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Alendronate Sodium as Enteric Coated Solid Lipid Nanoparticles; Preparation, Optimization, and In Vivo Evaluation to Enhance Its Oral Bioavailability

Treatment of osteoporosis with alendronate sodium has several challenges. The first challenge is the low bioavailability. The second main challenge is side effects, which include oesophageal ulceration. The aim of this research was to reformulate alendronate sodium as enteric coated solid lipid nano...

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Detalhes bibliográficos
Publicado no:PLoS One
Autor principal: Hosny, Khaled Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858199/
https://ncbi.nlm.nih.gov/pubmed/27148747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154926
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