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Enhanced Oral Bioavailability of Efavirenz by Solid Lipid Nanoparticles: In Vitro Drug Release and Pharmacokinetics Studies

Solid lipid nanoparticle is an efficient lipid based drug delivery system which can enhance the bioavailability of poorly water soluble drugs. Efavirenz is a highly lipophilic drug from nonnucleoside inhibitor category for treatment of HIV. Present work illustrates development of an SLN formulation...

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Detalhes bibliográficos
Main Authors: Gaur, Praveen Kumar, Mishra, Shikha, Bajpai, Meenakshi, Mishra, Anushika
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055422/
https://ncbi.nlm.nih.gov/pubmed/24967360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/363404
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