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Preparation, in vitro release, and pharmacokinetics in rabbits of lyophilized injection of sorafenib solid lipid nanoparticles

Sorafenib solid lipid nanoparticles (S-SLN) were prepared by emulsion evaporation–solidification at low temperature. Morphology was examined by transmission electron microscope. Particle size and zeta potential were determined by laser granularity equipment. Encapsulation efficiency (EE) was detecte...

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Detalhes bibliográficos
Main Authors: Zhang, Hong, Zhang, Fu-Ming, Yan, Shi-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391003/
https://ncbi.nlm.nih.gov/pubmed/22787390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S32415
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