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Preparation, Characterization, Pharmacokinetics and Tissue Distribution of Solid Lipid Nanoparticles Loaded with Tetrandrine

Tetrandrine (TET) is a poorly water-soluble bisbenzylisoquinoline alkaloid. In this study, TET solid lipid nanoparticles (SLNs) were prepared by a melt–emulsification and ultrasonication technique. Precirol(®) ATO 5, glyceryl monostearate, and stearic acid were used as the lipid matrix for the SLNs,...

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Bibliografiske detaljer
Main Authors: Li, Su, Ji, Zhaoshuai, Zou, MeiJuan, Nie, Xin, Shi, Yijie, Cheng, Gang
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167269/
https://ncbi.nlm.nih.gov/pubmed/21811889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9665-3
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