Characterization, pharmacokinetics, and hypoglycemic effect of berberine loaded solid lipid nanoparticles

The high aqueous solubility, poor permeability, and absorption of berberine (BBR) result in its low plasma level after oral administration, which greatly limits its clinical application. BBR solid lipid nanoparticles (SLNs) were prepared to achieve improved bioavailability and prolonged effect. Deve...

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Bibliografske podrobnosti
Main Authors: Xue, Mei, Yang, Ming-xing, Zhang, Wei, Li, Xiu-min, Gao, De-hong, Ou, Zhi-min, Li, Zhi-peng, Liu, Su-huan, Li, Xue-jun, Yang, Shu-yu
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2013
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3862509/
https://ncbi.nlm.nih.gov/pubmed/24353417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S51262
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