Berberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice

Berberine (BBR) shows very low plasma levels after oral administration due to its poor absorption by the gastrointestinal tract. We have previously demonstrated that BBR showed increased gastrointestinal absorption and enhanced antidiabetic effects in db/db mice after being entrapped into solid lipi...

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Dades bibliogràfiques
Publicat a:Int J Nanomedicine
Autors principals: Xue, Mei, Zhang, Liang, Yang, Ming-xing, Zhang, Wei, Li, Xiu-min, Ou, Zhi-min, Li, Zhi-peng, Liu, Su-huan, Li, Xue-jun, Yang, Shu-yu
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4531046/
https://ncbi.nlm.nih.gov/pubmed/26346310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S84565
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