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Berberine alleviates hyperglycemia by targeting hepatic glucokinase in diabetic db/db mice
Berberine (BBR) is a widely used anti-diabetic agent, and liver glucokinase (GK) has been reported to be involved. However, the mechanisms of BBR in regulating GK are still unknown. Here, we found that BBR upregulated GK immunofluorescence expression in AML12 cells cultured in high glucose and incre...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6541623/ https://ncbi.nlm.nih.gov/pubmed/31142783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44576-7 |
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