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Enhancing the Antitumor Activity of Berberine Hydrochloride by Solid Lipid Nanoparticle Encapsulation

Berberine hydrochloride (BH) is an isoquinolin alkaloid with promising anticancer efficacies. Nevertheless, further development and application of this compound had been hampered by its poor aqueous solubility, low gastrointestinal absorption, and rapid metabolism in the body. In this study, a solid...

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Hlavní autoři: Wang, Lu, Li, Hongtao, Wang, Shengpeng, Liu, Rong, Wu, Zhisheng, Wang, Chunming, Wang, Yitao, Chen, Meiwan
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113611/
https://ncbi.nlm.nih.gov/pubmed/24696391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0112-0
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