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Enhancing the Antitumor Activity of Berberine Hydrochloride by Solid Lipid Nanoparticle Encapsulation

Berberine hydrochloride (BH) is an isoquinolin alkaloid with promising anticancer efficacies. Nevertheless, further development and application of this compound had been hampered by its poor aqueous solubility, low gastrointestinal absorption, and rapid metabolism in the body. In this study, a solid...

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Detalhes bibliográficos
Main Authors: Wang, Lu, Li, Hongtao, Wang, Shengpeng, Liu, Rong, Wu, Zhisheng, Wang, Chunming, Wang, Yitao, Chen, Meiwan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113611/
https://ncbi.nlm.nih.gov/pubmed/24696391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0112-0
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