Immune complexes containing scleroderma-specific autoantibodies induce a profibrotic and proinflammatory phenotype in skin fibroblasts

BACKGROUND: In systemic sclerosis (SSc), autoantibodies provide the most accurate tool to predict the disease subset and pattern of organ involvement. Scleroderma autoantibodies target nucleic acids or DNA/RNA-binding proteins, thus SSc immune complexes (ICs) can embed nucleic acids. Our working hyp...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Arthritis Res Ther
Hoofdauteurs: Raschi, Elena, Chighizola, Cecilia Beatrice, Cesana, Laura, Privitera, Daniela, Ingegnoli, Francesca, Mastaglio, Claudio, Meroni, Pier Luigi, Borghi, Maria Orietta
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6116570/
https://ncbi.nlm.nih.gov/pubmed/30157947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1689-6
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items