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Diastereo- and enantioselective copper catalyzed hydroallylation of disubstituted cyclopropenes

A highly diastereo- and enantioselective protocol for the hydroallylation of 1,1- and 1,2-disubstituted cyclopropenes has been developed utilizing an in situ formed copper hydride. A variety of allyl electrophiles could be utilized yielding a diverse range of trisubstituted cyclopropanes. Finally a...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Sommer, Heiko, Marek, Ilan
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115688/
https://ncbi.nlm.nih.gov/pubmed/30310580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc02085j
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