Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment

Glucocorticoids (GCs) are metabolic hormones with immunosuppressive effects that have proven effective drugs against childhood acute lymphoblastic leukemia (ALL). Yet, the role of metabolic reprogramming in GC-induced ALL cell death is poorly understood. GCs efficiently block glucose uptake and meta...

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Publicat a:Cell Death Dis
Autors principals: Dyczynski, Matheus, Vesterlund, Mattias, Björklund, Ann-Charlotte, Zachariadis, Vasilios, Janssen, Jerry, Gallart-Ayala, Hector, Daskalaki, Evangelia, Wheelock, Craig E., Lehtiö, Janne, Grandér, Dan, Tamm, Katja Pokrovskaja, Nilsson, Roland
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113325/
https://ncbi.nlm.nih.gov/pubmed/30154400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0625-7
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