Identification of novel small molecules that inhibit STAT3-dependent transcription and function

Activation of Signal Transducer and Activator of Transcription 3 (STAT3) has been linked to several processes that are critical for oncogenic transformation, cancer progression, cancer cell proliferation, survival, drug resistance and metastasis. Inhibition of STAT3 signaling has shown a striking ab...

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Pubblicato in:PLoS One
Autori principali: Kolosenko, Iryna, Yu, Yasmin, Busker, Sander, Dyczynski, Matheus, Liu, Jianping, Haraldsson, Martin, Palm Apergi, Caroline, Helleday, Thomas, Tamm, Katja Pokrovskaja, Page, Brent D. G., Grander, Dan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479526/
https://ncbi.nlm.nih.gov/pubmed/28636670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178844
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