Loss of Wwox drives metastasis in triple-negative breast cancer by JAK2/STAT3 axis

Loss of WW domain-containing oxidoreductase (Wwox) expression has been observed in breast cancer (BC). However, its regulatory effects are largely unknown, especially in triple-negative breast cancer (TNBC). Herein, gene expression profiling revealed that JAK/STAT3 pathway was one of the most differ...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Chang, Renxu, Song, Lele, Xu, Yi, Wu, Yanjun, Dai, Cheng, Wang, Xinyu, Sun, Xia, Hou, Yingyong, Li, Wei, Zhan, Xianbao, Zhan, Lixing
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113304/
https://ncbi.nlm.nih.gov/pubmed/30154439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05852-8
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