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LKB1 obliterates Snail stability and inhibits pancreatic cancer metastasis in response to metformin treatment
Metastasis to distant organs is a particularly ominous feature of malignant cancer. LKB1 (also known as STK11) has been identified as a tumor suppressor in several types of cancers. Here, we show that LKB1 is at low levels and is negatively associated with poor clinical outcomes in pancreatic cancer...
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| Publicado no: | Cancer Sci |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5980291/ https://ncbi.nlm.nih.gov/pubmed/29601127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13591 |
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