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SORBS1 suppresses tumor metastasis and improves the sensitivity of cancer to chemotherapy drug

Tumor metastasis and invasion are both hallmarks of cancer malignancy and the leading cause of cancer death. Here we show that the adaptor protein SORBS1 (Sorbin and SH3 domain-containing protein 1, also known as CAP/ponsin) is expressed at low levels in clinical cancer samples. In addition, low-lev...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Song, Lele, Chang, Renxu, Dai, Cheng, Wu, Yanjun, Guo, Jingyu, Qi, Meiyan, Zhou, Wu, Zhan, Lixing
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354718/
https://ncbi.nlm.nih.gov/pubmed/27791200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12851
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