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Loss of Scribble Promotes Snail Translation through Translocation of HuR and Enhances Cancer Drug Resistance
Drug resistance of cancer cells to various therapeutic agents and molecular targets is a major problem facing current cancer research. The tumor suppressor gene Scribble encodes a polarity protein that is conserved between Drosophila and mammals; loss of the locus disrupts cell polarity, inhibits ap...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4697165/ https://ncbi.nlm.nih.gov/pubmed/26527679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.693853 |
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