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Variable deletion and duplication at recombination junction ends: Implication for staggered double-strand cleavage in class-switch recombination
Immunoglobulin class-switch recombination (CSR) gives rise to looped-out circular DNA of a cleaved S segment, which is lost eventually after cell divisions. To understand the molecular mechanism of S region cleavage during CSR, we constructed artificial CSR substrates in which inversion-type CSR tak...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC61132/ https://ncbi.nlm.nih.gov/pubmed/11717442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241524898 |
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