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Variable deletion and duplication at recombination junction ends: Implication for staggered double-strand cleavage in class-switch recombination

Immunoglobulin class-switch recombination (CSR) gives rise to looped-out circular DNA of a cleaved S segment, which is lost eventually after cell divisions. To understand the molecular mechanism of S region cleavage during CSR, we constructed artificial CSR substrates in which inversion-type CSR tak...

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Bibliografski detalji
Glavni autori: Chen, Xiaochuan, Kinoshita, Kazuo, Honjo, Tasuku
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2001
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC61132/
https://ncbi.nlm.nih.gov/pubmed/11717442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241524898
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