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Nanogel-mediated delivery of a cocktail of epigenetic drugs plus doxorubicin overcomes drug resistance in breast cancer cells
Epigenetic modifications (e.g., DNA methylation or histone deacetylation) are commonly implicated in cancer chemoresistance. We previously showed that pretreating resistant MCF-7/ADR breast cancer cells with a demethylating agent (5-aza-2′-deoxycytidine; DAC) or with an inhibitor of histone deacetyl...
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| Veröffentlicht in: | Drug Deliv Transl Res |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6113113/ https://ncbi.nlm.nih.gov/pubmed/29947019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-018-0556-y |
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