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Sustained Epigenetic Drug Delivery Depletes Cholesterol-Sphingomyelin Rafts from Resistant Breast Cancer Cells, Influencing Biophysical Characteristics of Membrane Lipids

Cell-membrane lipid composition can greatly influence biophysical properties of cell membranes, affecting various cellular functions. We previously showed that lipid synthesis becomes altered in the membranes of resistant breast cancer cells (MCF-7/ADR); they form a more rigid, hydrophobic lipid mon...

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Detalhes bibliográficos
Publicado no:Langmuir
Main Authors: Raghavan, Vijay, Vijayaraghavalu, Sivakumar, Peetla, Chiranjeevi, Yamada, Masayoshi, Morisada, Megan, Labhasetwar, Vinod
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725703/
https://ncbi.nlm.nih.gov/pubmed/26439800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.langmuir.5b02601
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