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Sustained Epigenetic Drug Delivery Depletes Cholesterol-Sphingomyelin Rafts from Resistant Breast Cancer Cells, Influencing Biophysical Characteristics of Membrane Lipids

Cell-membrane lipid composition can greatly influence biophysical properties of cell membranes, affecting various cellular functions. We previously showed that lipid synthesis becomes altered in the membranes of resistant breast cancer cells (MCF-7/ADR); they form a more rigid, hydrophobic lipid mon...

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Publicat a:Langmuir
Autors principals: Raghavan, Vijay, Vijayaraghavalu, Sivakumar, Peetla, Chiranjeevi, Yamada, Masayoshi, Morisada, Megan, Labhasetwar, Vinod
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725703/
https://ncbi.nlm.nih.gov/pubmed/26439800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.langmuir.5b02601
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