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Drug Resistance in Breast Cancer Cells: Biophysical Characterization of and Doxorubicin Interactions with Membrane Lipids

Understanding the role of lipids in drug transport is critical in cancer chemotherapy to overcome drug resistance. In this study, we isolated lipids from doxorubicin-sensitive (MCF-7) and -resistant (MCF-7/ADR) breast cancer cells to characterize the biophysical properties of membrane lipids (partic...

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Detalhes bibliográficos
Main Authors: Peetla, Chiranjeevi, Bhave, Radhika, Vijayaraghavalu, Sivakumar, Stine, Andrew, Kooijman, Edgar, Labhasetwar, Vinod
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997943/
https://ncbi.nlm.nih.gov/pubmed/20958074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100308n
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