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Drug Resistance in Breast Cancer Cells: Biophysical Characterization of and Doxorubicin Interactions with Membrane Lipids

Understanding the role of lipids in drug transport is critical in cancer chemotherapy to overcome drug resistance. In this study, we isolated lipids from doxorubicin-sensitive (MCF-7) and -resistant (MCF-7/ADR) breast cancer cells to characterize the biophysical properties of membrane lipids (partic...

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Autors principals: Peetla, Chiranjeevi, Bhave, Radhika, Vijayaraghavalu, Sivakumar, Stine, Andrew, Kooijman, Edgar, Labhasetwar, Vinod
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997943/
https://ncbi.nlm.nih.gov/pubmed/20958074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100308n
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