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Nanogel-mediated delivery of a cocktail of epigenetic drugs plus doxorubicin overcomes drug resistance in breast cancer cells
Epigenetic modifications (e.g., DNA methylation or histone deacetylation) are commonly implicated in cancer chemoresistance. We previously showed that pretreating resistant MCF-7/ADR breast cancer cells with a demethylating agent (5-aza-2′-deoxycytidine; DAC) or with an inhibitor of histone deacetyl...
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| Publicado no: | Drug Deliv Transl Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6113113/ https://ncbi.nlm.nih.gov/pubmed/29947019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-018-0556-y |
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