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Human Extrafollicular CD4(+) T Helper Cells Help Memory B Cells Produce Immunoglobulins

Follicular helper T (Tfh) cells are necessary for germinal center B cell maturation during primary immune responses; however, the T cells that promote humoral recall responses via memory B cells are less well defined. We herein characterize a human tonsillar CD4(+) T cell subset with this function....

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Kim, Sang Taek, Choi, Jin-Young, Lainez, Begona, Schulz, Vincent P., Karas, David E., Baum, Eric D., Setlur, Jennifer, Gallagher, Patrick G., Craft, Joe
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6112860/
https://ncbi.nlm.nih.gov/pubmed/30030323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701217
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