Advantage of a Narrow Spectrum Host Defense (Antimicrobial) Peptide Over a Broad Spectrum Analog in Preclinical Drug Development

The APO-type proline-arginine-rich host defense peptides exhibit potent in vitro killing parameters against Enterobacteriaceae but not to other bacteria. Because of the excellent in vivo properties against systemic and local infections, attempts are regularly made to further improve the activity spe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Chem
Egile Nagusiak: Ostorhazi, Eszter, Hoffmann, Ralf, Herth, Nicole, Wade, John D., Kraus, Carl N., Otvos Jr., Laszlo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2018
Gaiak:
Chemistry
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6111444/
https://ncbi.nlm.nih.gov/pubmed/30186829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00359
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