Preclinical advantages of intramuscularly administered peptide A3-APO over existing therapies in Acinetobacter baumannii wound infections

OBJECTIVES: The designer antibacterial peptide A3-APO is efficacious in mouse models of Escherichia coli and Acinetobacter baumannii systemic infections. Here we compare the efficacy of the peptide with that of imipenem and colistin in A. baumannii wound infections after burn injury. METHODS: CD-1 m...

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Detalhes bibliográficos
Main Authors: Ostorhazi, Eszter, Rozgonyi, Ferenc, Sztodola, Andras, Harmos, Ferenc, Kovalszky, Ilona, Szabo, Dora, Knappe, Daniel, Hoffmann, Ralf, Cassone, Marco, Wade, John D., Bonomo, Robert A., Otvos, Laszlo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980952/
https://ncbi.nlm.nih.gov/pubmed/20810424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkq337
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