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Intramuscularly Administered Peptide A3-APO Is Effective Against Carbapenem-Resistant Acinetobacter baumannii in Mouse Models of Systemic Infections

Most antibacterial peptides exhibit low therapeutic indices in vivo. Peptide A3-APO was shown to exhibit high potency against Escherichia coli bacteremia when added intraperitoneally. To extend the studies to systemic infections against multidrug-resistant organisms, we studied the efficacy of A3-AP...

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Detalles Bibliográficos
Publicado en:Biopolymers
Main Authors: Ostorhazi, Eszter, Rozgonyi, Ferenc, Szabo, Dora, Binas, Annegret, Cassone, Marco, Wade, John D., Nolte, Oliver, Bethel, Christopher R., Bonomo, Robert A., Otvos, Laszlo
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401472/
https://ncbi.nlm.nih.gov/pubmed/20564029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.21443
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