Preclinical advantages of intramuscularly administered peptide A3-APO over existing therapies in Acinetobacter baumannii wound infections

OBJECTIVES: The designer antibacterial peptide A3-APO is efficacious in mouse models of Escherichia coli and Acinetobacter baumannii systemic infections. Here we compare the efficacy of the peptide with that of imipenem and colistin in A. baumannii wound infections after burn injury. METHODS: CD-1 m...

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Hlavní autoři: Ostorhazi, Eszter, Rozgonyi, Ferenc, Sztodola, Andras, Harmos, Ferenc, Kovalszky, Ilona, Szabo, Dora, Knappe, Daniel, Hoffmann, Ralf, Cassone, Marco, Wade, John D., Bonomo, Robert A., Otvos, Laszlo
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980952/
https://ncbi.nlm.nih.gov/pubmed/20810424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkq337
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