Preclinical advantages of intramuscularly administered peptide A3-APO over existing therapies in Acinetobacter baumannii wound infections

OBJECTIVES: The designer antibacterial peptide A3-APO is efficacious in mouse models of Escherichia coli and Acinetobacter baumannii systemic infections. Here we compare the efficacy of the peptide with that of imipenem and colistin in A. baumannii wound infections after burn injury. METHODS: CD-1 m...

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Autors principals: Ostorhazi, Eszter, Rozgonyi, Ferenc, Sztodola, Andras, Harmos, Ferenc, Kovalszky, Ilona, Szabo, Dora, Knappe, Daniel, Hoffmann, Ralf, Cassone, Marco, Wade, John D., Bonomo, Robert A., Otvos, Laszlo
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980952/
https://ncbi.nlm.nih.gov/pubmed/20810424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkq337
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