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The closed form of Mad2 is bound to Mad1 and Cdc20 at unattached kinetochores
The spindle assembly checkpoint (SAC) ensures accurate chromosome segregation by delaying anaphase onset in response to unattached kinetochores. Anaphase is delayed by the generation of the mitotic checkpoint complex (MCC) composed of the checkpoint proteins Mad2 and BubR1/Bub3 bound to the protein...
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| 出版年: | Cell Cycle |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6110578/ https://ncbi.nlm.nih.gov/pubmed/29895228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1480209 |
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