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The closed form of Mad2 is bound to Mad1 and Cdc20 at unattached kinetochores
The spindle assembly checkpoint (SAC) ensures accurate chromosome segregation by delaying anaphase onset in response to unattached kinetochores. Anaphase is delayed by the generation of the mitotic checkpoint complex (MCC) composed of the checkpoint proteins Mad2 and BubR1/Bub3 bound to the protein...
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| Publicado no: | Cell Cycle |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6110578/ https://ncbi.nlm.nih.gov/pubmed/29895228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1480209 |
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