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The closed form of Mad2 is bound to Mad1 and Cdc20 at unattached kinetochores

The spindle assembly checkpoint (SAC) ensures accurate chromosome segregation by delaying anaphase onset in response to unattached kinetochores. Anaphase is delayed by the generation of the mitotic checkpoint complex (MCC) composed of the checkpoint proteins Mad2 and BubR1/Bub3 bound to the protein...

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Zhang, Gang, Nilsson, Jakob
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110578/
https://ncbi.nlm.nih.gov/pubmed/29895228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1480209
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