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Shugoshin is a Mad1/Cdc20-like interactor of Mad2
Mammalian centromeric cohesin is protected from phosphorylation-dependent displacement in mitotic prophase by shugoshin-1 (Sgo1), while shugoshin-2 (Sgo2) protects cohesin from separase-dependent cleavage in meiosis I. In higher eukaryotes, progression and faithful execution of both mitosis and meio...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3160248/ https://ncbi.nlm.nih.gov/pubmed/21666598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.187 |
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