The SMILE transcriptional corepressor inhibits cAMP response element–binding protein (CREB)–mediated transactivation of gluconeogenic genes

Under fasting conditions, activation of several hepatic genes sets the stage for gluconeogenesis in the liver. cAMP response element–binding protein (CREB), CREB-regulated transcription coactivator 2 (CRTC2), and peroxisome proliferator–activated receptor γ coactivator 1-alpha (PGC-1α) are essential...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Lee, Ji-Min, Han, Hye-Sook, Jung, Yoon Seok, Harris, Robert A., Koo, Seung-Hoi, Choi, Hueng-Sik
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2018
Teme:
Gene Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109926/
https://ncbi.nlm.nih.gov/pubmed/29950523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002196
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