The SMILE transcriptional corepressor inhibits cAMP response element–binding protein (CREB)–mediated transactivation of gluconeogenic genes

Under fasting conditions, activation of several hepatic genes sets the stage for gluconeogenesis in the liver. cAMP response element–binding protein (CREB), CREB-regulated transcription coactivator 2 (CRTC2), and peroxisome proliferator–activated receptor γ coactivator 1-alpha (PGC-1α) are essential...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Lee, Ji-Min, Han, Hye-Sook, Jung, Yoon Seok, Harris, Robert A., Koo, Seung-Hoi, Choi, Hueng-Sik
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2018
Onderwerpen:
Gene Regulation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109926/
https://ncbi.nlm.nih.gov/pubmed/29950523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002196
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