The SMILE transcriptional corepressor inhibits cAMP response element–binding protein (CREB)–mediated transactivation of gluconeogenic genes

Under fasting conditions, activation of several hepatic genes sets the stage for gluconeogenesis in the liver. cAMP response element–binding protein (CREB), CREB-regulated transcription coactivator 2 (CRTC2), and peroxisome proliferator–activated receptor γ coactivator 1-alpha (PGC-1α) are essential...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lee, Ji-Min, Han, Hye-Sook, Jung, Yoon Seok, Harris, Robert A., Koo, Seung-Hoi, Choi, Hueng-Sik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109926/
https://ncbi.nlm.nih.gov/pubmed/29950523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002196
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