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Molecular characterization of SMILE as a novel corepressor of nuclear receptors

SMILE (small heterodimer partner interacting leucine zipper protein) has been identified as a coregulator in ER signaling. In this study, we have examined the effects of SMILE on other NRs (nuclear receptors). SMILE inhibits GR, CAR and HNF4α-mediated transactivation. Knockdown of SMILE gene express...

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Autors principals: Xie, Yuan-Bin, Nedumaran, Balachandar, Choi, Hueng-Sik
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709580/
https://ncbi.nlm.nih.gov/pubmed/19429690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp333
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