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Molecular characterization of SMILE as a novel corepressor of nuclear receptors
SMILE (small heterodimer partner interacting leucine zipper protein) has been identified as a coregulator in ER signaling. In this study, we have examined the effects of SMILE on other NRs (nuclear receptors). SMILE inhibits GR, CAR and HNF4α-mediated transactivation. Knockdown of SMILE gene express...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709580/ https://ncbi.nlm.nih.gov/pubmed/19429690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp333 |
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