Ursodeoxycholic Acid Inhibits Liver X Receptor α-mediated Hepatic Lipogenesis via Induction of the Nuclear Corepressor SMILE

Small heterodimer partner interacting leucine zipper protein (SMILE) has been identified as a nuclear corepressor of the nuclear receptor (NRs) family. Here, we examined the role of SMILE in the regulation of nuclear receptor liver X receptor (LXRα)-mediated sterol regulatory element binding protein...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Ji-Min, Gang, Gil-Tae, Kim, Don-Kyu, Kim, Yong Deuk, Koo, Seung-Hoi, Lee, Chul-Ho, Choi, Hueng-Sik
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887176/
https://ncbi.nlm.nih.gov/pubmed/24265317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.491522
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