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Phosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcription
Modulation of the activity of the upstream binding factor (UBF) plays a key role in cell cycle-dependent regulation of rRNA synthesis. Activation of rDNA transcription on serum stimulation requires phosphorylation of UBF at serine 484 by G(1)-specific cyclin-dependent kinase (cdk)/cyclin complexes....
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC61092/ https://ncbi.nlm.nih.gov/pubmed/11698641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231071698 |
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