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Acetylation of UBF changes during the cell cycle and regulates the interaction of UBF with RNA polymerase I

The upstream binding factor UBF, an activator of RNA polymerase I transcription, is posttranslationally modified by phosphorylation and acetylation. We found that in NIH3T3 cells, UBF is acetylated in S-phase but not in G(1)-phase. To assess the role of acetylation in regulation of UBF activity, we...

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Библиографические подробности
Главные авторы: Meraner, Joachim, Lechner, Markus, Loidl, Adele, Goralik-Schramel, Maria, Voit, Renate, Grummt, Ingrid, Loidl, Peter
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421502/
https://ncbi.nlm.nih.gov/pubmed/16582105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl101
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