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Phosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcription

Modulation of the activity of the upstream binding factor (UBF) plays a key role in cell cycle-dependent regulation of rRNA synthesis. Activation of rDNA transcription on serum stimulation requires phosphorylation of UBF at serine 484 by G(1)-specific cyclin-dependent kinase (cdk)/cyclin complexes....

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Detalhes bibliográficos
Main Authors: Voit, Renate, Grummt, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC61092/
https://ncbi.nlm.nih.gov/pubmed/11698641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231071698
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