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Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription factor UBF.

The nucleolar factor UBF is phosphorylated by casein kinase II (CKII) at serine residues within the C-terminal acidic domain which is required for transcription activation. To investigate the biological significance of UBF modification, we have compared the trans-activating properties of cellular UB...

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Bibliografiske detaljer
Main Authors: Voit, R, Kuhn, A, Sander, E E, Grummt, I
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC307079/
https://ncbi.nlm.nih.gov/pubmed/7651819
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