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Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription factor UBF.
The nucleolar factor UBF is phosphorylated by casein kinase II (CKII) at serine residues within the C-terminal acidic domain which is required for transcription activation. To investigate the biological significance of UBF modification, we have compared the trans-activating properties of cellular UB...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1995
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307079/ https://ncbi.nlm.nih.gov/pubmed/7651819 |
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