Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription factor UBF.
The nucleolar factor UBF is phosphorylated by casein kinase II (CKII) at serine residues within the C-terminal acidic domain which is required for transcription activation. To investigate the biological significance of UBF modification, we have compared the trans-activating properties of cellular UB...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1995
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307079/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7651819/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.14.2593 |
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