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The genetic risk of Alzheimer’s disease beyond APOE ε4: systematic review of Alzheimer’s genetic risk scores

The ε4 allele of Apolipoprotein E (APOE) is the strongest known genetic risk factor of Alzheimer’s disease (AD) but does not account for the entirety of genetic risk. Genetic risk scores (GRSs) incorporating additional genetic variants have been developed to determine the genetic risk for AD, yet th...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Stocker, Hannah, Möllers, Tobias, Perna, Laura, Brenner, Hermann
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109140/
https://ncbi.nlm.nih.gov/pubmed/30143603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-018-0221-8
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