GAB2 Alleles Modify Alzheimer’s Risk in APOE ε4 Carriers

The apolipoprotein E (APOE) ε4 allele is the best established genetic risk factor for late-onset Alzheimer’s disease (LOAD). We conducted genome-wide surveys of 502,627 single-nucleotide polymorphisms (SNPs) to characterize and confirm other LOAD susceptibility genes. In ε4 carriers from neuropathol...

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Main Authors: Reiman, Eric M., Webster, Jennifer A., Myers, Amanda J., Hardy, John, Dunckley, Travis, Zismann, Victoria L., Joshipura, Keta D., Pearson, John V., Hu-Lince, Diane, Huentelman, Matthew J., Craig, David W., Coon, Keith D., Liang, Winnie S., Herbert, RiLee H., Beach, Thomas, Rohrer, Kristen C., Zhao, Alice S., Leung, Doris, Bryden, Leslie, Marlowe, Lauren, Kaleem, Mona, Mastroeni, Diego, Grover, Andrew, Heward, Christopher B., Ravid, Rivka, Rogers, Joseph, Hutton, Michael L., Melquist, Stacey, Petersen, Ron C., Alexander, Gene E., Caselli, Richard J., Kukull, Walter, Papassotiropoulos, Andreas, Stephan, Dietrich A.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587162/
https://ncbi.nlm.nih.gov/pubmed/17553421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.05.022
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