ASSOCIATION BETWEEN GAB2 HAPLOTYPE AND HIGHER GLUCOSE METABOLISM IN ALZHEIMER'S DISEASE-AFFECTED BRAIN REGIONS IN COGNITIVELY NORMAL APOEε4 CARRIERS

In a genome-wide association study (GWAS) of late-onset Alzheimer's disease (AD), we found an association between common haplotypes of the GAB2 gene and AD risk in carriers of the apolipoprotein E (APOE) ε4 allele, the major late-onset AD susceptibility gene. We previously proposed the use of f...

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Hauptverfasser: Liang, Winnie S., Chen, Kewei, Lee, Wendy, Sidhar, Kunal, Corneveaux, Jason J., Allen, April N., Myers, Amanda, Villa, Stephen, Meechoovet, Bessie, Pruzin, Jeremy, Bandy, Daniel, Fleisher, Adam S., Langbaum, Jessica B.S., Huentelman, Matthew J., Jensen, Kendall, Dunckley, Travis, Caselli, Richard J., Kaib, Susan, Reiman, Eric M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010232/
https://ncbi.nlm.nih.gov/pubmed/20888920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2010.09.066
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