Genetic Control of Human Brain Transcript Expression in Alzheimer Disease

We recently surveyed the relationship between the human brain transcriptome and genome in a series of neuropathologically normal postmortem samples. We have now analyzed additional samples with a confirmed pathologic diagnosis of late-onset Alzheimer disease (LOAD; final n = 188 controls, 176 cases)...

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Main Authors: Webster, Jennifer A., Gibbs, J. Raphael, Clarke, Jennifer, Ray, Monika, Zhang, Weixiong, Holmans, Peter, Rohrer, Kristen, Zhao, Alice, Marlowe, Lauren, Kaleem, Mona, McCorquodale, Donald S., Cuello, Cindy, Leung, Doris, Bryden, Leslie, Nath, Priti, Zismann, Victoria L., Joshipura, Keta, Huentelman, Matthew J., Hu-Lince, Diane, Coon, Keith D., Craig, David W., Pearson, John V., Heward, Christopher B., Reiman, Eric M., Stephan, Dietrich, Hardy, John, Myers, Amanda J.
Format: Artigo
Language:Inglês
Published: American Society of Human Genetics 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667989/
https://ncbi.nlm.nih.gov/pubmed/19361613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2009.03.011
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